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Comparison of L-FABP concentration in obese and lean men after one bout intensive aerobic exercise مقاله

نویسنده:

چکیده:

Introduction: Liver fatty acid binding protein (L-AFBP) is a novel biomarker of liver disease. Liver enzymes levels are higher in the obese than the lean people; however the effect of intensive aerobic exercise (IAE) on liver enzymes in the obese and the lean people not well known. Thus the aim of the present study was to comparison of L-FABP concentration in the obese and lean men after one bout IAE. Material & Methods: Nine sedentary obese men (BMI: 33.7 ± 2.1 kg/m2; ± SD) and nine sedentary lean men (BMI: 17.6 ± 1.6 kg/m2; ± SD) volunteered to participate in this study. All the subjects were performed the Bruce test as the intensive aerobic exercise. Blood samples were taken before and immediately after the IAE. Results: The results showed that alanine aminotransferase (ALT) was higher in obese group than the lean group at the baseline (P<0.05). L-AFBP decreased and ALT and aspartate aminotransferase (AST) increased after the IAE in the both groups (P<0.05). By comparison, the results indicated that the increase of ALT was higher in the obese group than the lean group (P<0.05); however, for L-AFBP and AST no significant differences were observed between two groups. Conclusions: One bout IAE increases AST and ALT and decreases L-AFBP in the obese men same as lean men.

خلاصه ماشینی:

Comparison of L-FABP concentration in obese and lean men after one bout intensive aerobic exercise Afsaneh Khazari1 and Ahmad Ahmadlu2* Received: 24 September 2017 / Accepted: 13 November 2017 (1) MS in Exercise physiology, Education Administration in Shiraz (2) PhD candidate in Exercise physiology, Education Administration in Shiraz (*) PhD candidate in Exercise physiology, Education Administration in Shiraz. Thus the aim of the present study was to comparison of L-FABP concentration in the obese and lean men after one bout IAE. Previously Ahmadlu and Moghadasi (2014) reported that L-FABP was decreased (P 20-min moderate-intensity exercise session (11), while Lira et al. Thus the aim of the present study was to comparison of liver enzymes concentration in the obese and lean men after one bout IAE. Previous studies indicated that the obesity is the main cause of elevated liver enzymes (3); however, our results indicated that no significant difference was at baseline for L-AFBP between obese group and lean group. Ahmadlu and Moghadasi (2014) reported that L-FABP was decreased (P Our results indicated that ALT was higher in obese group than the lean group at the baseline. In the present study, cells were damaged and serum level of enzymes increased significantly due to eccentric repeated contractions and long term exercise. 5. Conclusion In conclusion, the present study suggests that One bout IAE increases AST and ALT and decreases L-AFBP in the obese men same as lean men.

کلیدواژه ها:

AST ، ALT ، Liver function ، L-AFBP


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