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Effects of exercise intensity on RBP4 levels in female athletes مقاله

نویسنده:

چکیده:

<em>Introduction:Retinol-binding protein 4 (RBP4) has been described as an adipokine that contributes to insulin resistance, obesity and the metabolic syndrome. The aim of present study was to examine the effects of exercise intensity on RBP4 levels in female athletes.Material & Methods: 30 female karate athletics were randomly assigned to one of the High intensity training group (HIT, n=10), moderate intensity training group (MIT, n=10), or control group (n=10). The HIT training group performed endurance training 3 days a week for 8 weeks at an intensity corresponding to 75-80% individual maximum oxygen consumption for 45 min. The MIT group performed endurance training at the same days, times and duration at an intensity corresponding to 50-60% individual maximum oxygen consumption for 45 min.>Results: </em>Body mass and BMI increased (P<0.05) after 8 weeks HIT and MIT compared to the control group. For body fat percentage and maximal oxygen consumption there were no significant differences between the exercise groups and the control group. There were virtually no changes in body fat percentage, fasting glucose, insulin, insulin resistance and RBP4 levels after 8 weeks HIT and MIT.<br /> <em>Conclusions: </em>Serum RBP4 levels were not affected by 8 weeks HIT and MIT in female athletes.

خلاصه ماشینی:

com Abstract Introduction: Retinol-binding protein 4 (RBP4) has been described as an adipokine that contributes to insulin resistance, obesity and the metabolic syndrome. The aim of present study was to examine the effects of exercise intensity on RBP4 levels in female athletes. In fact, elevated serum RBP4 levels were associated with the components of metabolic syndrome in insulin-resistant subjects (6). (2006) reported that there was no significant change in RBP4 levels in obese women after 12 weeks moderate exercise training (8), while Lim et al. The purpose of this study was to examine the effects of 8 weeks HIT and MIT on serum RBP4 levels in female athletes. On the other hand, elevated RBP4 levels have been reported in subjects with insulin resistance and type 2 diabetes (6,9) whereas other studies showed no relationship between circulating RBP4, obesity, and insulin resistance (9,1,18). Our results showed that there was no significant relationship between RBP4 levels and insulin resistance determined by HOMA-IR. 5. Conclusion Our results showed that serum RBP4 levels were not affected by exercise intensity in female athletes. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes. Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes. Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes.

کلیدواژه ها:

RBP4 ، Exercise intensity ، Female Athletes ، Lipocalin


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